Mesothelioma Information

Tumor cells are rarely found mesotelial this very often or most often occurs in the pleura (more rarely in the peritoneum and other places). Mesothelioma is a tumor associated with asbestos exposure in the workplace in 90% of cases; but only 20% of all patients who suffered from pulmonary asbestosis. The risk of life (not influenced by smoking habits) in patients with severe exposure is 7-10% with a latent period between exposure and onset of tumor-25-45 years. Among the asbestos factory workers, carcinoma of the lung tumor is still the most frequently detected or most common, the risk of lung carcinoma experienced a noticeable increase if there is smoking.

Clinical Overview Mesothelioma patients found with complaints of chest pain, dyspnea and recurrent pleural effusions. Mesothelioma is a highly malignant tumor that invades the lungs and can metastasize widely. Some patients with these tumors are still able to survive or just over 2 years.
Morphology Tumor spread diffuse pulmonary fissures on the surface and thus tmembentuk sheath that surrounds the tumor. Epitelioid microscopic patterns of tumor (70%), sarkomatoid (20%) and mixed (biphasic) (10%).
• Pattern epitelioid showed similar cells-epithelium by forming tubular and papillary protrusions that resemble adenocarcinoma. Antigenic characteristics (kalretinin, WT-1 positivity and CK5 / 6) and ultrastructural (microvilli are long and slender) allows these tumors dihedakan with adenocarcinoma (MOC3I positivity and BG8 and have microvilli are short and fat).
• Polo sarkomatoid showed malignant cells resembling fibrosarcoma-shaped coil.

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